Nicotinamide Mononucleotide (NMN) is a molecule that has gained popularity in recent years due to its potential health benefits.
NMN is a fairly stable molecule; however, it is prone to degradation when exposed to temperatures over roughly 28 degrees Celsius. When exposed to temperatures above 28 degrees celsius, it can not only degrade and lose its potency, but transform into a molecule which can cause harm to the human body.
Along with the growth in the popularity of NMN has come an increase in people trying to make a quick profit from its sale, and as with any product there will always be a certain element of these people trying to cut corners and promote myths and gimmicks to sell the product.
One of these myths is that NMN can be stored at room temperature and not degrade. At every leg of the supply chain, from the manufacturer to the retailer, there is the opportunity for the product to be exposed to higher than recommended temperatures for extended periods of time.
This is before it has even arrived at the retailer. Unless there are strict protocols in place at every leg of the supply chain journey to keep the product under the recommended temperature of 28 degrees celsius, there is no guarantee that the NMN you receive will not be degraded.
Here's why NMN must be stored at low temperature:
- Stability: NMN is a fairly stable molecule; however, it is prone to degradation when exposed to temperatures over about 28 degrees Celsius. When exposed to these temperatures, it can break down and lose its potency, and transform into a molecule which can damage the body.
- Oxidation: NMN is an antioxidant that helps to protect cells from damage. However, when it is stored at high temperature, it can become oxidized and lose its ability to perform this function.
- Shelf life: NMN has a limited shelf life, and when stored improperly, it will degrade much faster. Keeping it frozen helps to extend its shelf life and ensure that it remains effective for a longer period of time.
Some companies have claimed to have developed a "shelf-stable" form of NMN, but the scientific evidence for this claim is limited. It is well established in the scientific literature that NMN is highly sensitive to heat and moisture, and needs to be stored in the freezer, so if the product you are purchasing doesn’t have these qualities, then its molecular structure has changed enough that it is no longer NMN.
While it is possible that some forms of NMN may be more stable than others, it is not currently possible to make a definitive statement about the stability of all forms of NMN without further research.
It is also important to note that the quality and purity of NMN can vary widely between different products and suppliers, so it is essential to research and choose a reputable source when purchasing NMN.
Remember; be very careful when purchasing ‘temperature stable’ NMN, and if need be ask whether the product has been kept at optimal temperature at every stage of it’s supply chain journey.
If you are considering adding NMN to your current regime, it is best to consult with a qualified healthcare professional before doing so.